Evaluation of the Efficacy of Crataegus oxyacantha in Dogs with Early-Stage Heart Failure (2020, Homeopathy)
-
Link: https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0040-1710021
-
Benefits claimed: In dogs with myxomatous mitral valve disease (MMVD), Crataegus oxyacantha (as mother tincture or 6 cH homeopathic form) reduces systolic blood pressure (faster in 6 cH at 60 days vs. 90 days for tincture), extends the asymptomatic phase of heart failure, and improves cardiac function via increased fractional shortening and isovolumetric relaxation time, making it a low-risk adjunct for hypertensive and cardiopathic dogs.
Therapeutic Efficacy of Carvedilol and Hawthorn Extract in Management of Dilated Cardiomyopathy in Dogs (2022, International Journal of Veterinary Sciences and Animal Husbandry)
-
Benefits claimed: Hawthorn extract (25 mg/kg bid, combined with standard therapy) improves clinical signs like exercise tolerance, cough, dyspnea, and polypnea; reduces pulmonary edema and left ventricular dimensions; enhances contractility indices (fractional shortening and ejection fraction); and prolongs survival (264.67 ± 41.22 days vs. shorter in carvedilol group), offering a cost-effective alternative for managing dilated cardiomyopathy (DCM) and improving quality of life.
Pharmaco-Toxicological Aspects of Herbal Drugs Used in Domestic Animals (2009, Natural Product Communications)
-
Link: https://journals.sagepub.com/doi/pdf/10.1177/1934578X0900401230
-
Benefits claimed: Hawthorn (Crataegus oxyacantha, in mother tincture with lemon balm and valerian at 1 drop/kg bid-tid) alleviates anxiety, reduces stress, and controls behavioral or psychological problems in pets including dogs; it is classified as highly safe (AHPA Class 1) with a large margin of safety, supporting its use as an adjunctive therapy for emotional health.