Dietary Supplementation with Methylsulfonylmethane and Myo-Inositol Supports Hair Quality and Fecal Microbiome in Poodles (2024, Animals)
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Benefits claimed: MSM supplementation (0.2% in diet) increased sulfur content in hair, reduced hair scale thickness for smoother coat quality, positively altered fecal microbiota (e.g., increased Gammaproteobacteria and Glucerabacter, reduced Proteobacteria), and influenced carbohydrate metabolism, suggesting improvements in skin/coat health and gut microbiome balance in dogs.
Study of the effectiveness of Flexirun (joint nutraceutical) for the treatment of dogs with hip osteoarthritis: A prospective, block-randomized clinical trial (2024, The Pharma Innovation Journal)
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Link: https://www.thepharmajournal.com/archives/2024/vol13issue9/PartC/13-9-35-930.pdf
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Benefits claimed: MSM (250 mg/tablet, as part of Flexirun) contributed to faster symptom relief when combined with carprofen, sustained improvements in LOAD scores after NSAID discontinuation, reduced pain and lameness, and provided anti-inflammatory and antioxidant effects, enhancing mobility and quality of life in dogs with hip OA without relapse.
Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement (2017, Nutrients)
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Benefits claimed: MSM supplementation improves health outcomes including reduced inflammation, joint/muscle pain, and oxidative stress; it supports antioxidant defenses and is safe for animal use, with potential applications for managing OA and joint conditions in dogs based on extrapolated animal data.