A randomized, double-blind, prospective, placebo-controlled study of the efficacy of a diet supplemented with curcuminoids extract, hydrolyzed collagen and green tea extract in owner's dogs with osteoarthritis (2017, BMC Veterinary Research)
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Benefits claimed: In dogs with naturally occurring OA, the curcuminoids-supplemented diet (over 3 months) reduced pain at manipulation, stabilized pain severity scores (unlike worsening in controls), and improved the ability to rise from lying down, suggesting anti-inflammatory effects that enhance mobility and quality of life as an adjunct therapy, with no serious adverse events.
In vitro and in vivo activity of liposome-encapsulated curcumin for naturally occurring canine cancers (2018, Veterinary and Comparative Oncology)
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Benefits claimed: Liposome-encapsulated curcumin inhibited tumor cell proliferation in canine cancer cell lines and achieved stable disease in 4/6 dogs completing infusions in a pilot trial, claiming anti-cancer and anti-angiogenic effects that could address poor bioavailability, with potential for intravenous therapy in cancer-bearing dogs.
Dog food production using curcumin as antioxidant: effects of intake on animal growth, health and feed conservation (2020, Archives of Animal Nutrition)
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Benefits claimed: Curcumin (32.9 mg/kg in feed over 42 days) enhanced antioxidant enzyme activity, reduced reactive oxygen species and inflammation (e.g., lower lymphocytes and globulins), improved red/white blood cell counts, and boosted total antioxidant capacity, supporting overall health and oxidative stress reduction in young dogs, while also aiding feed preservation.